“During the preovulatory period, both I3C and TAM blocked normal LH and follicle-stimulating hormone ( FSH ) surges and suppressed serum progesterone (P(4)) profoundly without changing circulating levels of estrogen (E(2)).”
“In summary, both I3C and TAM block ovulation by altering preovulatory concentrations of LH and FSH , but I3C appears to exert its effect(s) by (a) different mechanism(s) of action.”