supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
supplement:
Indole-3-Carbinol
Research Papers that Mention the Interaction
“In mice … the chemopreventive agents , lung tumor multiplicity was significantly reduced to 6.3 + or - 2.2, 4.9 + or - …, 4.8 + or - 1.9 and 3.6 + or - 1.4 by PEITC-NAC plus I3C , PEITC-NAC plus MI, I3C plus MI …-NAC plus I3C plus MI, respectively.”
Inhibition of lung carcinogenesis and critical cancer-related signaling pathways by N-acetyl-S-(N-2-phenethylthiocarbamoyl)-l-cysteine, indole-3-carbinol and myo-inositol, alone and in combination.“However, the chemopreventive activity is dependent on the dose of I3C , and at low doses which do not induce CYP1A activity, there is evidence for increased IQ-DNA adduct formation in vivo.”
The disposition and metabolism of 2-amino-3-methylimidazo-[4,5-f]quinoline in the F344 rat at high versus low doses of indole-3-carbinol.
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback