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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
drug:
Imipramine
supplement:
Vitamin C
Research Papers that Mention the Interaction
“Sub-effective dose of ascorbic acid combined with sub-effective doses of fluoxetine, imipramine , bupropion, MK-801 or 7-nitroindazole produced a synergistic antidepressant-like effect in mice exposed or not to TNF-α.”
TNF-α-induced depressive-like phenotype and p38MAPK activation are abolished by ascorbic acid treatment“Apomorphine proved to be the most effective compound, fully antagonizing the effect of ascorbic acid at a concentration of 10 −6 M. A partial inhibition of the effect of ascorbic acid was induced by 10 −4 M serotonin, desipramine, imipramine and LSD.”
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