“5 Our findings suggest that PLC is the target for IMI, that recovery of IM needs lipid phosphorylation for PIP2 resynthesis, and that IMI inhibits IM by activating a PLC‐dependent pathway, likely by decreasing the concentration of PIP2.”
“Also, when we applied phosphatidylinositol 4,5‐bisphosphate (PIP2) intracellularly, it diminished the inhibition of IM by IMI.”