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Last Updated: 2 years ago

Possible Interaction: Imipramine and Magnesium

supplement:

Magnesium

Research Papers that Mention the Interaction

Moreover, the joint administration of Mg and imipramine (IMI) at ineffective doses per se, resulted in a potent reduction in the immobility time in this test.
Pharmacological reports : PR  •  2006  |  View Paper
Mg doses ineffective per se (5 and 10 mg/kg) given jointly with IMI also at ineffective doses (10 and 15 mg/kg) resulted in a potent reduction in the immobility time.
Moreover administration of IMI increased (normalized) magnesium brain concentration, without influence on the serum level.
The present data demonstrated an enhancement of the antidepressant-like effect by joint administration of IMI and magnesium in the FST, and further indicate the particular role of magnesium in the antidepressant action.
Pharmacology Biochemistry and Behavior  •  2005  |  View Paper
Magnesium uptake from media containing 5 mM‐sodium is inhibited by amiloride, quinidine and imipramine.
The Journal of physiology  •  1991  |  View Paper
Mg 2+ ATPase and Na + −K + ATPase activities of the sarcolemmal fraction, whereas imipramine decreased calcium binding, Ca 2+ ATPase and Mg 2 + ATPase activities.
Biochemical pharmacology  •  1980  |  View Paper
In the literature there are reports concerning pharmacological studies in which a potentiation of the effects has been observed after a co-administration of antidepressant imipramine and magnesium.
Polimery w medycynie  •  2014  |  View Paper