Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago

Possible Interaction: Imipenem and Serine

drug:

Imipenem

supplement:

Serine

Research Papers that Mention the Interaction

“In contrast, L-amino-acids behaved differently: In assays with IMI , 9 out of 13 isomers were ineffective whereas 3 were antagonistic (L-phenylalanine, L-serine , L-tryptophan).”
Modulation of antimicrobial effects of beta-lactams by amino acids in vitro.
Zentralblatt fur Bakteriologie : international journal of medical microbiology  •  1991  |  View Paper
“Of the antibiotics tested, both cefoxitin and N-formimidoyl thienamycin (N-f-thienamycin) were capable of antagonism in Ser.”
In-vitro antagonism by N-formimidoyl thienamycin and cefoxitin of second and third generation cephalosporins in Aeromonas hydrophila and Serratia marcescens.
The Journal of antimicrobial chemotherapy  •  1983  |  View Paper
“Cefoxitin and N-formimidoylthienamycin are potent anti-bacterial agents; they effectively inactivate the serine R39 enzyme and, to a lesser extent, the serine R61 enzyme.”
Interaction between non-classical beta-lactam compounds and the Zn2+-containing G and serine R61 and R39 D-alanyl-D-alanine peptidases.
The Biochemical journal  •  1981  |  View Paper