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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Imidazole
supplement:
Cupric Cation
Research Papers that Mention the Interaction
“These results indicated that the ternary complex is formed in the Cu transport process from the albumin to the amino acid, but His imidazole nitrogen in the fourth-binding site of Cu(II) strongly resists the replacement by the incoming ligand.”
Transport of Cu(II) from an albumin mimic peptide, GlyGlyHisGly, to histidine and penicillamine.“For the first time it was clearly demonstrated that a polymeric displacer [poly(VI-VCL)] was more efficient compared to a monomeric displacer (imidazole) of the same chemical nature, probably due to the multipoint interaction of imidazole groups within the same macromolecule with one Cu2+ ion.”
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