“Interestingly, KRGE also enhanced the cytotoxic and apoptotic effect of IM in KBM‐5 cells.”
“Our results demonstrate that KRGE can enhance the anticancer activity of IM and may have a substantial potential in the treatment of CML.”
“The combination treatment of KRGE and IM caused pronounced suppression of p38 and signal transducer and activator of transcription 5 phosphorylation and induced phosphorylation of p53 compared with the individual treatment.”