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Last Updated: 3 years ago

Possible Interaction: Ifenprodil and D-Serine

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drug:

Ifenprodil

supplement:

D-Serine

Research Papers that Mention the Interaction

“On the other hand, the antidepressant-like effect of ifenprodil (20mg/kg) was reversed by N-methyl-d-aspartic acid (an agonist at the glutamate site, 75mg/kg) or d-serine (an agonist at the glycine site, 100nmol/mouse).”

Effects of ifenprodil on the antidepressant-like activity of NMDA ligands in the forced swim test in mice

Progress in Neuro-Psychopharmacology and Biological Psychiatry • 2013 | View Paper

“This effect of d-serine was inhibited by a variety of NMDA receptor antagonists (ketamine, MK 801 and ifenprodil ), suggesting that NMDA receptors are involved in the effects of d-serine on the neurogenic relaxation of corporal tissue strips.”

d-Serine modulates neurogenic relaxation in rat corpus cavernosum.

Biochemical pharmacology • 2010 | View Paper

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