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Discover Supplement-Drug Interactions

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Last Updated: 4 months ago

Possible Interaction: Idoxuridine and Tretinoin

supplement:

Tretinoin

Research Papers that Mention the Interaction

Retinoic acid RA ) was found to inhibit induction of virus by 5-iododeoxyuridine , cycloheximide, and histidinol; inhibition was concentration (10(-4) to 10(-6) M) and time dependent (1 to 7 hr) and not a consequence of cytotoxicity.
Using synchronized cells, it was found that 5 X 10(-5) M RA added in G1 phase and followed by cycloheximide or 5-iododeoxyuridine induction inhibited virus expression 60 and 84%, respectively.
Cancer research  •  1981  |  View Paper