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Discover Supplement-Drug Interactions

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Last Updated: 3 months ago

Possible Interaction: Idarubicin and Triptolide Analog

Research Papers that Mention the Interaction

Combination index-isobologram analysis indicates a synergistic effect between TPL and IDA , which inhibits the colony-forming ability of LSC-like cells and induces their apoptosis.
Low dose of TPL enhances the cytotoxicity of idarubicin (IDA) in LSCs.
Our findings indicate that the synergistic cytotoxicity of TPL and IDA in LSCs-like cells may attribute to both induction of ROS and inhibition of the Nrf2 and HIF-1α pathways.
Cell Death and Disease  •  2013  |  View Paper
RESULTS A synergistic effect was observed when triptolide was added to idarubicin or to AraC to induce apoptosis of THP-1 leukemic cells.
Experimental hematology  •  2008  |  View Paper