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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Ibuprofen
supplement:
Ferric Ion
Research Papers that Mention the Interaction
“The quantitative analysis of the Fe-K edge extended X-ray absorption fine structure (EXAFS) signals and modeling of the near edge (XANES) spectral features demonstrated that warfarin and ibuprofen binding modify the local structure of the heme-Fe(III).”
The Five-To-Six-Coordination Transition of Ferric Human Serum Heme-Albumin Is Allosterically-Modulated by Ibuprofen and Warfarin: A Combined XAS and MD Study“ Ibuprofen and tolmetin, two other prostaglandin synthetase inhibitors, also inhibit the interaction of Fe++ with arachidonic acid suggesting this may be a general mechanism for this type of drug.”
Inhibition of ferrous iron induced oxidation of arachidonic acid by indomethacin.
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