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Last Updated: 3 years ago

Possible Interaction: Ibuprofen and Allyl Isothiocyanate

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drug:

Ibuprofen

supplement:

Allyl Isothiocyanate

Research Papers that Mention the Interaction

“Ibuprofen‐acyl glucuronide, but not ibuprofen , inhibited calcium responses evoked by reactive TRPA1 agonists, including allyl isothiocyanate ( AITC ), in cells expressing the recombinant and native human channel and in cultured rat primary sensory neurons.”

The acyl‐glucuronide metabolite of ibuprofen has analgesic and anti‐inflammatory effects via the TRPA1 channel

Pharmacological research • 2019 | View Paper

“Interestingly, the TRPA1 antagonist HC-030031 and the cyclo-oxygenase (COX) inhibitor ibuprofen inhibited not only AITC but also carrageenan-induced edema.”

TRPA1 Contributes to the Acute Inflammatory Response and Mediates Carrageenan-Induced Paw Edema in the Mouse

Scientific reports • 2012 | View Paper

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