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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
drug:
Hypochlorite
supplement:
3-Chlorotyrosine
Research Papers that Mention the Interaction
“ Cl-Tyr and diCl-Tyr were also formed from free tyrosine but then reacted further with HOCl.”
Reactions of Hypochlorous Acid with Tyrosine and Peptidyl-tyrosyl Residues Give Dichlorinated and Aldehydic Products in Addition to 3-Chlorotyrosine*“The kinetic rate constants for the reaction of 3-chlorotyrosine with HOCl , histidine chloramine, or lysine chloramine to form 3,5-dichlorotyrosine are reported.”
“noted that 3-chlorotyrosine is degraded by HOCl , calling into question its use as a biomarker.”
“Detection of chlorotyrosine has the potential to unequivocally identify the contribution hypochlorous acid makes to inflammation.”
“Therefore, chlorotyrosine will be a specific marker for the production of hypochlorous acid in vivo and for the involvement of myeloperoxidase in inflammatory tissue damage.”
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