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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Hydroxyproline
drug:
Olmesartan
Research Papers that Mention the Interaction
“Although the combination therapy with olmesartan and compound 21 led to blood pressure levels, PWV, and wall thickness comparable to olmesartan-alone–treated rats, only in the combination group was complete prevention of increased hydroxyproline deposition achieved, resulting in even more pronounced stiffness reduction.”
“ Olmesartan completely prevented hypertension, PWV and wall thickness increase, and the increase of aortic stiffness and partly prevented hydroxyproline accumulation.”
Direct Angiotensin II Type 2 Receptor Stimulation in N&ohgr;-Nitro-L-Arginine-Methyl Ester–Induced Hypertension: The Effect on Pulse Wave Velocity and Aortic Remodeling“ Liver hydroxyproline content, the mRNA expression of collagen α1(I) and α‐smooth muscle actin (α‐SMA), and plasma levels of transforming growth factor‐β1 (TGF‐β1) were significantly reduced by olmesartan treatment, suggesting that olmesartan improved liver fibrosis.”
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