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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Hydroxyproline
drug:
Methylprednisolone
Research Papers that Mention the Interaction
“The hydroxyproline content was significantly less in the methyl-prednisolone and the iloprost groups (p<0.05).”
Effects of iloprost on bleomycin-induced pulmonary fibrosis in rats compared with methyl-prednisolone.“Our results demonstrate that treatment with antioxidant drugs such as vitamin E and methylprednisolone decreased tissue HP levels, and thus inhibited new collagen synthesis and stricture formation in rats with alkali-induced caustic esophageal burns.”
“RESULTS Me hylprednisolone tr eatment significantly decreased TGF-beta and IGF-I levels in the wound fluid and hyd roxyproline co ntent in the tissue (P<.05).”
“ Methylprednisolone decreased wound DNA to 21%, hydroxyproline to 30%, and total protein to 5% of the values found in saline-infused controls.”
“ Methylprednisolone treatment at the time of sponge implantation reduced the content of both hydroxyproline and hemoglobin and caused a clearly reduced RNA/DNA ratio in the new connective tissue.”
“The hydroxyproline concentration in pulmonary tissue was significantly decreased in N. sativa and methylprednisolone groups compared to the bleomycin group in both prevention groups (p<0.001).”
Early and late preventive effect of Nigella sativa on the bleomycin-induced pulmonary fibrosis in rats: An experimental study
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