Allen Institute for Artificial Intelligence logo

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 7 months ago

Possible Interaction: Hydroxyproline and Diacerein



Research Papers that Mention the Interaction

UNLABELLED ANIMAL MODEL OF DEGENERATIVE JOIN DISEASE: A mouse model … joint disease with an induced granuloma has demonstrated that diacerein inhibits loss of hydroxyproline and proteoglycans in joint cartilage, an effect not observed with conventional nonsteroidal antiinflammatory drugs (NSAID) or with a specific inhibitor of cyclooxygenase-2 (COX-2).
Presse medicale  •  2002  |  View Paper
In the ovariectomized rats, diacerein (10, 100 mg/kg/day) also significantly prevented bone loss and reduced the serum alkaline phosphatase and decreased the excretion of urinary hydroxyproline.
European journal of pharmacology  •  2002  |  View Paper