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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Hydroxyproline
drug:
Diacerein
Research Papers that Mention the Interaction
“UNLABELLED ANIMAL MODEL OF DEGENERATIVE JOIN DISEASE: A mouse model … joint disease with an induced granuloma has demonstrated that diacerein inhibits loss of hydroxyproline and proteoglycans in joint cartilage, an effect not observed with conventional nonsteroidal antiinflammatory drugs (NSAID) or with a specific inhibitor of cyclooxygenase-2 (COX-2).”
[Comparison of the pharmacologic effect of diacerein and a selective COX-2 inhibitor in the mouse induced-granuloma model].“In the ovariectomized rats, diacerein (10, 100 mg/kg/day) also significantly prevented bone loss and reduced the serum alkaline phosphatase and decreased the excretion of urinary hydroxyproline.”
Pharmacological studies of diacerein in animal models of inflammation, arthritis and bone resorption.
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