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Discover Supplement-Drug Interactions

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Last Updated: 7 months ago

Possible Interaction: Hydroxyproline and Diacerein

supplement:

Hydroxyproline

Research Papers that Mention the Interaction

UNLABELLED ANIMAL MODEL OF DEGENERATIVE JOIN DISEASE: A mouse model … joint disease with an induced granuloma has demonstrated that diacerein inhibits loss of hydroxyproline and proteoglycans in joint cartilage, an effect not observed with conventional nonsteroidal antiinflammatory drugs (NSAID) or with a specific inhibitor of cyclooxygenase-2 (COX-2).
Presse medicale  •  2002  |  View Paper
In the ovariectomized rats, diacerein (10, 100 mg/kg/day) also significantly prevented bone loss and reduced the serum alkaline phosphatase and decreased the excretion of urinary hydroxyproline.
European journal of pharmacology  •  2002  |  View Paper