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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Hydroxyproline and Collagenases

Research Papers that Mention the Interaction

Modification with chitosan/riboflavin increased the mechanical properties, enhanced the mechanical stability of demineralized dentin substrates against hydrolytic and/or collagenolytic degradation challenges and decreased HYP release with collagenase exposure.
Journal of the mechanical behavior of biomedical materials  •  2013  |  View Paper
Collagenase injections significantly increased hydroxyproline excretion.
Advances in gerontology = Uspekhi gerontologii  •  2019  |  View Paper
However, no hydroxyproline is detectable in 17k protein, and it is extensively degraded with bacterial collagenase.
Experimental hematology  •  1990  |  View Paper
Further treatment of the trypsinized cells with collagenase resulted in a decrease of hydroxyproline in both samples of cell to negligible values.
Experimental gerontology  •  1968  |  View Paper
In this paper, it is shown that injection of collagenase in lateral brain ventricles of rats increases the level of hydroxyproline (hypro) in the CSF, suggesting that collagen is indeed degraded by the enzyme.
Neurochemical Research  •  2004  |  View Paper