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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Hydroxychloroquine
supplement:
Calcium Supplement
Research Papers that Mention the Interaction
“In isolated human neutrophils, treatment with hydroxychloroquine resulted in reduced mobilisation of intracellular calcium , diminished concentration of external oxidants and in decreased phosphorylation of Ca(2+)-dependent protein kinase C isoforms PKCα and PKCβII, which regulate activation of NADPH oxidase on plasma membrane.”
Selective inhibition of extracellular oxidants liberated from human neutrophils--A new mechanism potentially involved in the anti-inflammatory activity of hydroxychloroquine.“In contrast, within 5 days 400 mg of hydroxychloroquine daily lowered elevated levels of calcium and 1,25-(OH)2D by 37% and 72%, respectively, in a hypercalcemic patient with sarcoidosis.”
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