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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Hydroxocobalamin
drug:
Sodium Thiosulfate
Research Papers that Mention the Interaction
“ Hydroxocobalamin is an effective first‐line antidote used mainly in monotherapy of cyanide poisonings, while the opinions are different on the effects of its combination with sodium thiosulfate.”
Successful Use of Hydroxocobalamin and Sodium Thiosulfate in Acute Cyanide Poisoning: A Case Report with Follow‐up“However, we disagree that sodium thiosulphate adds to the effectiveness of hydroxocobalamin.”
“However, we disagree that sodium thiosulphate adds to the effectiveness of hydroxocobalamin.”
“Further, sodium thiosulfate was not found to be effective when added to hydroxocobalamin in the treatment of cyanide-induced shock.”
Hydroxocobalamin versus sodium thiosulfate for the treatment of acute cyanide toxicity in a swine (Sus scrofa) model.“Sodium nitrite did not modify the toxicity of the cyanohydrin, but sodium thiosulfate, hydroxocobalamin and their combination were antagonistic.”
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