Possible Interaction: Hydrogen Peroxide and Tannins

“The lipid peroxidation of red cell membrane induced by H2O2 was decreased significantly by tannic acid at a concentration of 5 micrograms/ml.”

“Ubiquitin, methyl gallate and tannic acid are able to prevent H2O2 from inhibiting the 26S activity.”

“ GT pretreatment has also inhibited the depletion of cellular NAD+ pools in hydrogen peroxide‐ or peroxynitrite‐treated HaCaT cells.”

“ TA and its related compounds decreased the DNA strand breaks induced by Trp-P-2, PhIP or H2O2 at concentrations of 0.1-10 microg/ml.”

“In addition, addition of H2O2 trigger fast release of CuII as a result of oxidation of galloyl groups in TA.”

“The capsules functionalised with TA exhibit a higher scavenging capacity for hydrogen peroxide and hydroxyl radicals, suggesting that the external layer of TA shows intrinsic antioxidant properties, and represents a valid strategy to increase the overall antioxidant potential of the developed capsules.”

“The spreading-inhibitory effect of TA at high concentrations overcame the induction of spreading by other stimuli, including phorbol 12-myristate 13-acetate, hydrogen peroxide , denatured fibrinogen surfaces, and naked plastic surfaces.”

“Pre‐incubation of cultured murine astrocytes with as little as 100 nM gallotannin produced significant reductions in H2O2‐induced cell death assessed both 24 and 72 h after H2O2 exposure.”

“These TAs all inhibit to various degrees ornithine decarboxylase (ODC) induction, hydroperoxide (HPx) production and the sequential stimulation of RNA, protein and DNA synthesis linked to TPA promotion.”

“The results showed that tannic acid had a much higher H2O2 scavenging activity than that of L-apple acid.”