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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Hydrogen Peroxide
supplement:
Sphingosine 1-Phosphate
Research Papers that Mention the Interaction
“ H2O2 also reversed the beneficial effects of S1P in alleviating IR.”
Hepatic insulin resistance induced by mitochondrial oxidative stress can be ameliorated by sphingosine 1-phosphate“In addition, ASPP 092 attenuated the increase in reactive oxygen species production and the decrease in total glutathione level induced by H2O2.”
“Treatment with H2O2 at 400 µM for 12 h caused 79 % C6 astroglial cell death which was significantly reduced to 37 % by pretreatment with ASPP 092 (5 µM).”
Protective Effects of a Diarylheptanoid from Curcuma comosa Against Hydrogen Peroxide-Induced Astroglial Cell Death.“Both Sase and SPP significantly decreased Ca2+ recovery of PC12 cells after H2O2 exposure.”
“Exogenous sphingosine 1-phosphate S1P ) stimulated hydrogen peroxide (H2O2) generation in association with an increase in intracellular Ca2+ concentration in FRTL-5 thyroid cells.”
“We conclude that S1P stimulates H2O2 generation through a PLC-Ca2+ system and also inhibits adenylyl cyclase in FRTL-5 thyroid cells.”
“Exogenous S1P led to stomatal closure and H2O2 production, and the effects of S1P were largely prevented by the H2O2 modulators ascorbic acid, catalase, and diphenyleneiodonium.”
Sphingosine-1-phosphate (S1P) mediates darkness-induced stomatal closure through raising cytosol pH and hydrogen peroxide (H2O2) levels in guard cells in Vicia faba“Exogenous sphingosine 1-phosphate S1P ) stimulated hydrogen peroxide (H2O2) generation in association with an increase in intracellular Ca2+ concentration in FRTL-5 thyroid cells.”
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