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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Hydrogen Peroxide and Serine

supplement:

Serine

Research Papers that Mention the Interaction

We provide evidence that H2O2 suppresses NF-κB export by prolonging polyubiquitination of signaling intermediaries, which promotes Ser phosphorylation and destabilization of newly synthesized IκBα proteins.
Journal of Biological Chemistry  •  2008  |  View Paper
Hydrogen peroxide (1 mm) markedly induced tyrosine phosphorylation of focal adhesion kinase (FAK) and serine phosphorylation of Akt at 1 h after stimulation.
The Journal of Biological Chemistry  •  1999  |  View Paper
Moreover, H2O2 treatment to the cultures caused membranous translocation of G-protein-coupled receptor kinase 2 (GRK 2) and increased serine phosphorylation of D1A receptors accompanied by an increase in protein kinase C (PKC) activity.
Free radical biology & medicine  •  2006  |  View Paper
Also, H2O2 induced serine (Ser)‐727 phosphorylation of Stat1 but not Stat3.
Journal of neurochemistry  •  2005  |  View Paper
H2O2 significantly induced threonine (Thr) phosphorylation of Cx46 and Cx50, and serine (Ser) phosphorylation of Cx50.
Molecular vision  •  2004  |  View Paper
In addition, intrathecal injection of D‐serine greatly increased spinal H2O2 levels by 80.0% and 56.9% in Swiss and Balb/c mice respectively, but reduced spinal H2O2 levels by 29.0% in C57 mice.
Pharmacology research & perspectives  •  2021  |  View Paper