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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Hydrogen Peroxide
supplement:
S-Allylcysteine
Research Papers that Mention the Interaction
“In both cell lines, SAC exhibited dose-dependent inhibition of H2O2 formation.”
S-allyl cysteine reduces oxidant load in cells involved in the atherogenic process.“ SAC consistently exhibited a dose-dependent inhibition of NF-kappa B activation induced by both TNF-alpha and H2O2.”
“Further, SAC treatment dose dependently inhibited H2O2 induced apoptosis via decreasing the Bax/Bcl-2 ratio, restoring mitochondrial membrane potential (∆Ψm), inhibiting mitochondrial cytochrome c release, and inhibiting proteolytic cleavage of caspase-3.”
“ SAC protected cells from H2O2 induced oxidative damage by inhibiting reactive oxygen species accumulation and lipid peroxidation.”
“This study demonstrates that S-allyl cysteine (SAC) renders cytoprotective effects on H2O2 induced oxidative damage and apoptosis in HepG2 cells.”
“ SAC supplementation also suppressed the rise in cytokines levels (TWEAK/IL6/myostatin) caused by H2O2.”
S-allyl cysteine: A potential compound against skeletal muscle atrophy.“In contrast, SAC has much lower scavenging activity against H2O2 , or NO.”
“AGE and SAC exhibited dose dependent inhibition of both LDH release and TBA-RS production induced by 50 microM of H2O2.”
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