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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Hydrogen Peroxide
supplement:
Phosphatidic Acid
Research Papers that Mention the Interaction
“ H2O2 stimulated the formation of phosphatidic acid and the accumulation of phosphatidylbutanol, a product of the phospholipase D (PLD)‐catalyzed transphosphatidylation reaction.”
“Purified phosphatidic acid PA ) also increased intracellular H2O2 and the increase was inhibited by the catalase.”
Lysophosphatidic acid increases intracellular H2O2 by phospholipase D and RhoA in rat-2 fibroblasts.“Furthermore, preincubation with PA blocked the subsequent Ca2+ response to H2O2 , and the incubation with H2O2 also blocked the PA-induced rise of [Ca2+] i .”
“Thus, it was suggested that PA stimulated Ca2+ release from PA-sensitive, but not inositol 1,4,5-trisphosphate-sensitive, Ca2+ stores by the activation of RhoA and intracellular H2O2.”
“As a product of PLD, phosphatidic acid PA ) substantially enhanced H2O2 production and stomatal closure in wide type, pldα1, and cuaoζ.”
Copper amine oxidase and phospholipase D act independently in abscisic acid (ABA)-induced stomatal closure in Vicia faba and Arabidopsis
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