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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Hydrogen Peroxide
supplement:
Phenethyl Isothiocyanate
Research Papers that Mention the Interaction
“Furthermore, activation of JNK1 by PEITC was inhibited by pro-oxidants hydrogen peroxide and diamide, although these two pro-oxidants by themselves had opposing effects on JNK1 activity.”
Phenethyl isothiocyanate, a natural chemopreventive agent, activates c-Jun N-terminal kinase 1.“Treatment with PEITC increased the expression of antioxidative enzymes regulated by Nrf2 such as γ-glutamylcysteine-synthetase, heme oxygenase 1, NAD(P)H:quinone oxidoreductase 1 and glutathione S-transferase, and reduced oxidative stress induced by H2O2.”
Phenethyl isothiocyanate protects against H2O2-induced insulin resistance in 3T3-L1 adipocytes“Results showed that SFN and PEITC were able to counteract ROS production induced by H2O2.”
Neuroprotective potential of isothiocyanates in an in vitro model of neuroinflammation
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