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Last Updated: 2 years ago

Possible Interaction: Hydrogen Peroxide and NADH

supplement:

NADH

Research Papers that Mention the Interaction

Generation of the free radical O2•– and H2O2 by eGFP in the presence of NADH affects the gene expression of cells.
Redox biology  •  2017  |  View Paper
We showed that H2O2 initiates and maintains NADH oxidation and O2-uptake but is also necessary for the formation of superoxide anion and hydroxyl radicals.
Biochemical and biophysical research communications  •  1979  |  View Paper
Furthermore, an inhibitory effect of NADH on metHb formation was observed with additions of oxidants such as H2O2 , NO, and NaNO2.
ACS chemical biology  •  2017  |  View Paper
H2O2 (0.2–5 mM) moderately depolarized mitochondria, halted their intracellular trafficking in a Ca2+- and cAMP-independent manner, and directly oxidized cellular nicotinamide adenine dinucleotide ( NADH ) and flavin adenine dinucleotide (FADH2).
Pflügers Archiv - European Journal of Physiology  •  2009  |  View Paper
Recently it has been shown that NADH can be considered an important antioxidant as it reacts with peroxyl and alkoxyl radicals under in vitro conditions.
Folia morphologica  •  2009  |  View Paper
We have previously demonstrated that when cardiac mitochondria were challenged with H2O2, NADH production and oxidative phosphorylation declined.
Biochemistry  •  2008  |  View Paper
They inhibited NADH production by acting specifically on aconitase for and alpha-ketoglutarate dehydrogenase for H2O2 and HO•. Our results show that , H2O2 and HO• act on different mitochondrial targets to alter ATP synthesis, mostly through inhibition of NADH production.
Free radical research  •  2007  |  View Paper
Addition of NADH or NADPH increased H2O2 production by a factor of 3 and 5, respectively.
Experientia  •  2005  |  View Paper
Mutation of an NADH peroxidase-encoding gene resulted in the enhanced accumulation of hydrogen peroxide.
Infection and Immunity  •  2004  |  View Paper
Alterations in NADH levels induced by H2O2 closely paralleled changes in the rate of state 3 respiration.
The Journal of Biological Chemistry  •  2001  |  View Paper
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