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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
drug:
Hydrogen Peroxide
supplement:
Mn3+
Research Papers that Mention the Interaction
“Oxidized Mn, as both aqueous Mn(III) and Mn(III/IV) oxides, was only observed in the presence of active catalase, indicating that hydrogen peroxide (H2O2), a product of the reaction of O2− with Mn(II), inhibits the oxidation process presumably through the reduction of Mn(III).”
“While complexing ligands played a role in stabilizing Mn(III), they did not eliminate the inhibition of net Mn(III) formation by H2O2.”
Constraints on superoxide mediated formation of manganese oxides“In contrast to effective Mn(II) chelators, low-affinity ligands supported considerably slower enzyme turnover, and Mn(III) released was more reactive with hydrogen peroxide , resulting in a catalase-type reaction.”
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