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“Moreover, combination of Met with Ss significantly upregulated hydrogen peroxide (H2O2) production and phagocytic capacity, but significantly downregulated the production of IL-1β, iNOS activity and killing capacity.”
International immunopharmacology • 2019 | View Paper
“Copper ions as well as added hydrogen peroxide are found to oxidize the methionine residue, but notably, this oxidative modification occurs only in the aggregated HTT but not in the soluble state.”
The Journal of Biological Chemistry • 2012 | View Paper
“Finally, oxidation of methionines by H2O2 greatly inhibited alpha-Syn fibrillation in vitro, leading to the formation of relatively stable oligomers, which are not toxic to dopaminergic and GABAergic neurons.”
“Therefore, the different effects of free methionine , acetylcysteine, and glutathione on the rates of oxidation of methionine residues in G-CSF are consistent with their different reactivity toward oxidation by H2O2.”
“Addition of either ascorbate, gallate, caffeate or hydrogen peroxide to the culture medium stimulated the oxidation of free methionine to methionine sulfoxide, regardless of the presence or absence of the cells.”
“Incubation of IPF ELF with AKD cells in the presence of H2O2 caused increased cellular injury (P less than 0.01 compared with control), which was suppressed by methionine , a myeloperoxidase system scavenger.”