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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Hydrogen Peroxide
supplement:
Lycopene
Research Papers that Mention the Interaction
“Furthermore, LYC mitigated ATR-induced dysregulation of oxidative stress markers by reducing MDA, H2O2 levels, and increasing SOD, GPx, CAT concentration, and Nrf2 activation.”
Lycopene Triggers Nrf2-AMPK Cross Talk to Alleviate Atrazine-Induced Nephrotoxicity in Mice.“Similarly, lycopene significantly diminished the apoptosis ratio of oxidative injured cells, and also downregulated the expressions of p53 and caspase-3 mRNA induced by H2O2.”
“ Lycopene significantly reduced the genotoxicity and mutagenicity of H2O2 in all of the conditions tested.”
“ LYC could effectively induce autophagy in the H2O2 treatment group, and this effect could be attenuated by 3‐MA.”
Activation of autophagy contributes to the protective effects of lycopene against oxidative stress‐induced apoptosis in rat chondrocytes“Furthermore, LYC inhibited oxidative stress induced by AFB1 via decreasing the levels of reactive oxygen species (ROS), hydrogen peroxide ( H2O2 ) and malondialdehyde (MDA), while enhancing the total antioxidant capacity (T-AOC) and antioxidant enzyme activities.”
“ Lycopene (10 mg/kg body weight for 6 days) pretreatment attenuated lipid peroxidation and prohibited the excessive synthesis of hydrogen peroxide.”
“The LYC increased mGSH concentration and GSH-Px and MnSOD activities, and decreased H2O2 and ROS concentrations compared to AFB1 group (P < 0.05).”
Protective effects of lycopene on mitochondrial oxidative injury and dysfunction in the liver of aflatoxin B1-exposed broilers
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