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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Hydrogen Peroxide
supplement:
Kaempferol
Research Papers that Mention the Interaction
“Results The results showed luteolin significantly inhibited LPS-induced leukocyte adhesion, hydrogen peroxide production and mast cell degranulation, and increased intestinal microcirculation blood flow and ameliorated pathological changes in the mesenteric artery and the small intestine.”
“In vivo studies showed that KFL decreased inflammation and lipid peroxidation and increased H2O2 scavenging and biochemical marker enzyme expression.”
“ Kaempferol also inhibits the upregulated vascular endothelial growth … (VEGF) mRNA expression levels induced by H2O2 in ARPE-19 cells and affects the oxidation and antioxidant imbalanced system in ARPE-19 cells treated … H2O2 through the regulations of both the activities of reactive oxygen species (ROS) and superoxide dismutase (SOD).”
“The results showed that luteolin treatment significantly increased the viability of HaCaT cells upon exposure to hydrogen peroxide , and the administration of luteolin in vivo significantly improved skin flap survival in the I/R injury rat model.”
Protective effect of luteolin on skin ischemia-reperfusion injury through an AKT-dependent mechanism“Additionally, an intracellular calcium rise and subsequent mitochondrial membrane potential collapse, P53 phosphorylation, reduced BcL-2/Bax ratio in the mitochondrial membrane, release cytochrome c from mitochondria, leading to the subsequent activation of caspase 3 activation by H2O2 were all markedly suppressed in the presence of luteolin.”
“Both quercetin and kaempferol significantly inhibited the hydrogen peroxide (H2O2)-induced EA.hy926 cell injury and intracellular reactive oxygen species (ROS) generation.”
“ Luteolin (Lu) and quercetin (Qu) increased the expression of catalase and reduced H2O2 levels, but without an observed change in the protein levels of MnSOD.”
“ Luteolin and o-coumaric acid may attend in scavenging of hydrogen peroxide , whereas quercetin, apigenin and (+)-catechin probably participate in reduction of superoxide anion radical content.”
Role of phenolic compounds during antioxidative responses of winter triticale to aphid and beetle attack.“The results demonstrated that luteolin was able to inhibit the reduction in cell viability induced by H2O2.”
“Quercetin and luteolin reduced the oxidative damage, especially that caused by hydrogen peroxide.”
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