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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
drug:
Hydrogen Peroxide
supplement:
Epigallocatechin
Research Papers that Mention the Interaction
“ Hydrogen peroxide generated in the medium contributed to the cytotoxicity of PG, EGCG and Q to human prostate carcinoma DU-145 cells, since catalase increased the survival of the cells subjected to these compounds in vitro.”
Dietary antioxidants as a source of hydrogen peroxide.“Moreover, EGCG attenuated the reduced activation and expression of ERK, p38 MAPK, and Akt induced by H2O2.”
“The ability of EGCG to block the accumulation of intracellular reactive oxygen species and the loss of mitochondrial membrane potential (Δψm) induced by H2O2 was examined with dichlorofluorescein (DCF) fluorescence and 5,5′,6,6'-tetrachloro-1,1',3,3′-tetrathylbenzimidazol carbocyanine iodide (JC-1).”
“Conclusions Taken together, our results demonstrate that EGCG inhibits UVA-induced H2O2 production, mitogen-activating protein kinase activation, and expression of COX-2.”
“ EGCG generated a larger amount of hydrogen peroxide than EC in a dose-dependent manner.”
Inhibition of gap junctional intercellular communication by the green tea polyphenol (-)-epigallocatechin gallate in normal rat liver epithelial cells.“Treatment of D. radiodurans with different TrxR inhibitors such as ebselen, epigallocatechin gallate and auranofin displayed this organism sensitivity to H2O2 treatment in a concentration-dependent manner.”
Understanding the survival mechanisms of Deinococcus radiodurans against oxidative stress by targeting thioredoxin reductase redox system
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