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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Hydrogen Peroxide
supplement:
Egb 761
Research Papers that Mention the Interaction
“Moreover, a marked increase in intracellular free radical generation was found after the H2O2 administration which could be reversed almost completely by EGb761 , indicating that inhibition of free radical generation is an important mechanism of the anti-apoptosis action of EGb761.”
EGb761 Protects Hydrogen Peroxide-induced Death of Spinal Cord Neurons through Inhibition of Intracellular ROS Production and Modulation of Apoptotic Regulating Genes“While several antioxidants failed to block H2O2-induced apoptosis of these cells, Ginkgo biloba extract EGb ) totally prevented the cell death and growth inhibition induced by H2O2.”
“Concomitant application of EGb 761 with H2O2 resulted in similar but less reduction.”
“ EGB and EGB CS can reduce the production of ROS in BMSCs exposed to H2O2.”
Ginkgo Biloba L. Extract Reduces H2O2-Induced Bone Marrow Mesenchymal Stem Cells Cytotoxicity by Regulating Mitogen-Activated Protein Kinase (MAPK) Signaling Pathways and Oxidative Stress“Compared with vehicle-treated cells, pretreatment with EGb 761 significantly enhanced the survival of neurons exposed to tertiary butylhydroperoxide (t-BuOOH), hydrogen peroxide ( H2O2 ), and N-methyl-D-aspartate (NMDA).”
“Furthermore, EGb761 also inhibited caspase-3 activity induced by H2O2.”
“It is concluded that EGb761 has protective effect on bovine vascular endothelial cells against damage induced by H2O2.”
“The viability of bovine aortic endothelial cells (BAECs) treated with 0.1 m M H2O2 was decreased by 39.8%, and 100 mg/l EGb761 increased the viability by 20.6%.”
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