supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
drug:
Hydrogen Peroxide
supplement:
Delphinidin
Research Papers that Mention the Interaction
“Furthermore, pre-incubation of ARPE-19 cells with delphinidin markedly inhibited the intracellular reactive oxygen species (ROS) generation and Nox1 protein expression induced by H2O2.”
“MTT (3-(4,5-dimethylthiazol-2-yl)-2,… that pretreatment of ARPE-19 cells with delphinidin (25, 50, and 100 … the apoptosis from H2O2 (0.5 mM)-induced oxidative stress in a concentration-dependent manner, which was … c, and caspase-3 protein expression and enhancement of Bcl-2 protein.”
Protective effects of delphinidin against H2O2–induced oxidative injuries in human retinal pigment epithelial cells“In the absence of catalase, the accumulated hydrogen peroxide appears to play a substantial role for the observed DNA-damaging properties of delphinidin and the apparent lack of antioxidative properties of this anthocyanidin.”
“Furthermore, the incubation with delphinidin (DEL) or GA resulted in a substantial formation of hydrogen peroxide.”
“However, high concentration of hydrogen peroxide (100 µM) downregulated p27 in both cell lines, but delphindin , one of antioxidative anthocyanins, enhanced the level of p27 suppressed by 100 µM hydrogen peroxide.”
Significance of p27kip1 as potential biomarker for intracellular oxidative status
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback