“Inflammation factors, such as matrix metallopeptidase 13 (Mmp13), tissue inhibitor of metalloproteinase 1 (Timp1), and interleukin‐6 (Il6), were downregulated in the H2O2 group with AP , demonstrating a decrease in the progression of OA.”
“This study indicates that AP exerts protection effects on oxidative stress via activation of the Keap1–Nrf2–Are pathway in chondrocytes injured by H2O2 , which may be promising for the therapy of OA.”