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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Hydrogen Peroxide and Alpha-Ketoglutaric Acid

Research Papers that Mention the Interaction

Conversely, in NNT-deficient BL/6J mitochondria, H2O2 emission is higher with α-KG than with P/M as substrate, and further potentiated by complex I blockade.
Basic Research in Cardiology  •  2020  |  View Paper
We report that TCA cycle metabolites (citrate, isocitrate, α-ketoglutarate , fumarate, malate) individually and quickly inhibit H2O2 release.
Journal of bioenergetics and biomembranes  •  2011  |  View Paper
A study of the isocitrate dehydrogenase reaction in H218O was made possible by the observation that decarboxylation of α-ketoglutarate by H2O2 was faster than spontaneous exchange of the keto group with the medium.
The Journal of biological chemistry  •  1966  |  View Paper