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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Hydrocortisone
supplement:
Melatonin
Research Papers that Mention the Interaction
“Seven subjects exhibited an entrained or shortened cortisol period during melatonin treatment.”
The Effects of Low-Dose 0.5-mg Melatonin on the Free-Running Circadian Rhythms of Blind Subjects“Contemporaneous administration of melatonin antagonized the phase advances of the cortisol and BT(c) rhythms, as well as the melatonin peak and melatonin offset.”
“In three of the subjects, cortisol was shown to be phase-shifted in tandem with the melatonin rhythm.”
“In younger mothers, MN and polymorphonuclear (PMN) colostrum phagocytes exhibited higher rates of G. lamblia elimination when treated with both melatonin and cortisol.”
“ Melatonin influences the release of growth hormone and cortisol in humans, and it was recently reported that it promoted bone formation.”
“Immunosuppression with cortisol injection in young ducks decreased the density of the melatonin binding sites in the thymus.”
“Furthermore, the expected hypocalcemic response to cortisol injection is prevented by melatonin.”
“ Melatonin has been reported to suppress adrenocorticotropin (ACTH) secretion in the anterior pituitary and cortisol production in the adrenal by different mechanisms.”
“Dysregulation of the relationships between MEL and LH, E2, FT3 and cortisol found in girls with AN might affect the balance of the OPG/sRANKL system.”
“Interactions between cortisol and melatonin hormones might be involved in the development of chronic exhaustion.”
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