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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Hydrocortisone
supplement:
Marijuana
Research Papers that Mention the Interaction
“Many other psychoactive drugs can affect the HPA axis, not just stimulants such as cocaine, but also relaxants such as cannabis and their regular use may also differentially affect hair deposits of cortisol.”
Psychoactive drug influences on hair cortisol“Furthermore, compared to non-users, the early and late onset cannabis users had higher levels of cortisol at 8 p.m. (OR = 1.25, 95% CI: 1.03-1.53 and OR = 1.21, 95% CI: 1.01-1.45, respectively).”
“Findings indicate acute MJ administration typically raises cortisol levels, but this increase is blunted in MJ-dependent users relative to controls.”
“There is mixed evidence for how MJ use affects basal cortisol levels and the CAR.”
Marijuana Use and Hypothalamic-Pituitary-Adrenal Axis Functioning in Humans
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