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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Hydrocortisone
supplement:
Licorice
Research Papers that Mention the Interaction
“Its congenital absence or inhibition by licorice increases cortisol levels at the mineralocorticoid receptor, causing mineralocorticoid effects.”
“The liquorice therefore leads to an increase in cortisol and through its mineralocorticoid effect increased blood pressure.”
“The liquorice therefore leads to an increase in cortisol and through its mineralocorticoid effect increased blood pressure.”
“Excessive ingestion of licorice induces a syndrome of hypokalemia and hypertension that reflects increased activation of renal mineralocorticoid receptors by cortisol.”
“It has been shown that licorice inhibits 11 beta-dehydrogenase, preventing local inactivation of cortisol and allowing cortisol inappropriate access to intrinsically nonspecific renal mineralocorticoid receptors.”
“ Liquorice extract has been claimed to induce inhibition of the activity of 11 beta-hydroxysteroid dehydrogenase which converts cortisol to cortisone.”
Effect of glycyrrhizine on hyperkalemia due to hyporeninemic hypoaldosteronism in diabetes mellitus.
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