Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: a year ago

Possible Interaction: Hydrocodone and Quinine

supplement:

Quinine

Research Papers that Mention the Interaction

In vivo, quinine (20 mg/kg) and budipine (10 mg/kg) produced a marked suppression in brain and plasma hydromorphone levels detected after the peripheral administration of hydrocodone , thus confirming that the doses used suppressed CYP2D1 activity.
The effects of quinine on the locomotor activating effects of hydrocodone were subtle at best.
The Journal of pharmacology and experimental therapeutics  •  1997  |  View Paper