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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Hydrocodone
supplement:
Quinine
Research Papers that Mention the Interaction
“In vivo, quinine (20 mg/kg) and budipine (10 mg/kg) produced a marked suppression in brain and plasma hydromorphone levels detected after the peripheral administration of hydrocodone , thus confirming that the doses used suppressed CYP2D1 activity.”
“The effects of quinine on the locomotor activating effects of hydrocodone were subtle at best.”
Effect of cytochrome P450 2D1 inhibition on hydrocodone metabolism and its behavioral consequences in rats.
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