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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Hydrocodone and Quinine



Research Papers that Mention the Interaction

In vivo, quinine (20 mg/kg) and budipine (10 mg/kg) produced a marked suppression in brain and plasma hydromorphone levels detected after the peripheral administration of hydrocodone , thus confirming that the doses used suppressed CYP2D1 activity.
The effects of quinine on the locomotor activating effects of hydrocodone were subtle at best.
The Journal of pharmacology and experimental therapeutics  •  1997  |  View Paper