Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Hydrochlorothiazide and Serum Albumin, Human

Research Papers that Mention the Interaction

Both secondary and tertiary structures of HSA have been affected upon HCTZ binding.
It looks like that both secondary and tertiary structures of HSA have been affected upon HCTZ binding.
The results of fluorescence titration experiments revealed that HCTZ strongly quenches the intrinsic fluorescence of HSA through a static quenching mechanism.
The surface hydrophobicity index of HSA was decreased upon HCTZ binding.
Journal of pharmaceutical and biomedical analysis  •  2019  |  View Paper