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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Hydralazine
supplement:
Ascorbate
Research Papers that Mention the Interaction
“We have observed that in fibroblasts from patients with this duplication mutation, administration of hydralazine , an iron-chelating agent, and ascorbate , a cofactor for LH activity, stimulates LH activity and its mRNA significantly more than in other EDS VI patients who do not have this duplication.”
A common duplication in the lysyl hydroxylase gene of patients with Ehlers Danlos syndrome type VI results in preferential stimulation of lysyl hydroxylase activity and mRNA by hydralazine.
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