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“In vitro studies showed that the flavonoid aglycones apigenin, luteolin and kaempferol inhibited the hyaluronidase activity of five different venoms dose-dependently.”
“ Kaempferol , quercetin, myricetin, and rutin in flavonols inhibited hyaluronidase reaction specifically, while apigenin, luteolin, baicalin, and baicalein in flavones showed specific inhibition to collagenase reaction.”
“The plant natural products namely tannic acid and the flavonoids luteolin, kaempferol and apigenin exerted potent inhibition on the hyaluronidase enzyme.”