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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Apigenin
Research Papers that Mention the Interaction
“In vitro studies showed that the flavonoid aglycones apigenin , luteolin and kaempferol inhibited the hyaluronidase activity of five different venoms dose-dependently.”
Inhibitory effects of flavonoids on several venom hyaluronidases“When the oocyte-cumulus complex was incubated with sperm protein extracts or capacitated epididymal sperm in the presence of the hyaluronidase inhibitor apigenin , dispersal of cumulus cells from the cumulus was effectively inhibited.”
Hyaluronan-degrading activity of mouse sperm hyaluronidase is not required for fertilization?“Conversely, apigenin , a hyaluronidase inhibitor, blocked PH-20 hyaluronidase activity 93% without inhibiting sperm-zona binding.”
“The hyaluronidase activities of both enzymes could be inhibited by apigenin.”
“The plant natural products namely tannic acid and the flavonoids luteolin, kaempferol and apigenin exerted potent inhibition on the hyaluronidase enzyme.”
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