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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
drug:
Human Calcitonin
supplement:
Calcium Supplement
Research Papers that Mention the Interaction
“… HCT (1.0 mU/min·100 g body wt) to … reduced the urinary fractional excretion rate of water, Mg, Ca and K. At the tip of the long-looped nephrons, the fractional delivery of water … the presence of HCT, although the glomerular filtration rate of these nephrons was unaltered.”
Effects of human calcitonin on water and electrolyte movements in rat juxtamedullary nephrons: inhibition of medullary K recycling“In cTAL segments, PTH and hCT significantly stimulated the reabsorption of Na+, Cl−, Ca2+ and Mg2+.”
“The infusion of 1 nM hCT decreased the plasma calcium concentration by 18% in old and by 29% in young female rats.”
“ Human calcitonin (hCT) caused a decrease in the release of calcium and magnesium.”
“In the urine, HCT markedly reduced Ca and Mg excretion whereas excretion of water, Na and K was not significantly affected.”
“It is concluded that HCT stimulated Na, Cl, Ca and Mg reabsorption.”
Stimulation by human calcitonin of electrolyte transport in distal tubules of rat kidney“The hCT injection significantly decreased the plasma calcium concentration in young female rats, compared to old female rats at 10, 30, and 60 min after the injection.”
“Two hrs after hCT injection, the urinary calcium concentration decreased greater (p less than 0.01) in young than in old female rats.”
“In these rats, hCT decreased magnesium (Mg) and calcium (Ca) excretion in a dose-dependent fashion.”
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