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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Homocysteine
supplement:
Vitamin D
Research Papers that Mention the Interaction
“The tHcy value was significantly lower (p < 0.001) in young women with CC or CT of MTHFR than with TT (10.9+/-4.7 micromol/L) (n =250).”
“There was a significant negative correlation between the levels of vitamin D and homocysteine in TT (r = -0.357, P < 0.01).”
“There was significant negative correlation of homocysteine with vitamin D and B12 in postmenopausal non-osteoporotic and homocysteine with vitamin B12 in postmenopausal osteoporotic females.”
Interplay of vitamin D, vitamin B12, homocysteine and bone mineral density in postmenopausal females“This study presents a parallel decrease of homocysteine and ferritin in response to regular training supported by vitamin D supplementation.”
“In both groups, the average level of Hcy was lower in individuals carrying CC of (rs1801198) than in those with CG+GG (both P< 0.05).”
“These observations suggest that temporal improvements in vitamin D status reduce serum homocysteine concentrations, and therefore may potentially contribute to the primary prevention of CVD.”
“With spline, in a univariate model, an increase in 25(OH)D was associated with a significant decrease in homocysteine [-0.56 (-0.75 to -0.37) μmol/L] until 25(OH)D reaches but not if above its median (21 ng/mL).”
“… homocysteine … 25(OH)D remain significant [-0.49 (-0.67 to -0.31) μmol/L] only below the population median of 25(OH)D. CONCLUSIONS From a … an inverse relation between 25(OH)D and homocysteine among those with 25(OH)D concentration of 21 ng/mL or less.”
“In subgroups with homocysteine concentrations >or= 9 micro mol/L, risk tended to be higher in CC than in TT subjects.”
“The present study shows an independent inverse linear relationship between vitamin D and Hcy values.”
“We observed an inverse linear relationship between lower levels of vitamin D and higher Hcy (r = − 0.092, p < 0.001) and a higher prevalence of hyperhomocysteinemia in patients with lower quartiles values of vitamin D (p < 0.001).”
Association between vitamin D deficiency and serum Homocysteine levels and its relationship with coronary artery disease“There were significant interactions based on sex between 25(OH)D and Hcy (p = 0.003), creatinine (p = 0.004), uric acid (p = 0.040), and HbA1c (p = 0.037).”
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