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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Homocysteine and Tolbutamide

supplement:

Homocysteine

Research Papers that Mention the Interaction

Homocysteine also dose-dependently inhibited insulinotropic responses to a range of glucose-dependent secretagogues including nutrients (alanine, arginine, 2-ketoisocaproate), hormones (glucagon-like peptide-1 (7-36)amide, gastric inhibitory polypeptide and cholecystokinin-8), neurotransmitter (carbachol), drug ( tolbutamide ) as well as a depolarising concentration of KCl or elevated Ca2+.
The Journal of endocrinology  •  2006  |  View Paper
Insulinotropic responses to alanine, arginine, 2-ketoisocaproate, elevated Ca2+, tolbutamide , potassium chloride (KCl), forskolin, and phorbol 12-myristate 13-acetate were also significantly reduced by homocysteine.
Pancreas  •  2007  |  View Paper