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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
supplement:
Homocysteine
drug:
Tetrahydrofolate
Research Papers that Mention the Interaction
“The reduced folate derivative methyl-tetrahydrofolate participates in the methylation of homocysteine to form methionine.”
Serum folate and homocysteine levels in head and neck squamous cell carcinoma“Indeed, we observed …; the decrease of methyl-tetrahydrofolate … homocysteine and S-adenosylhomocysteine concentrations, which are normally maintained at very low values, shifting the methylation index (S-adenosylmethionine/S-adenosylhomocysteine … by a factor of 3 the activity of the Mg-protoporphyrin IX methyltransferase (CHLM), an essential enzyme for chlorophyll synthesis.”
C1 metabolism and chlorophyll synthesis: the Mg-protoporphyrin IX methyltransferase activity is dependent on the folate status.
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