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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Homocysteine
drug:
Rosuvastatin
Research Papers that Mention the Interaction
“Also, to explore whether rosuvastatin can alter the abnormal secretion and activation of MMP-2 and TIMP-2 and migration of VSMCs induced by homocysteine.”
Effects of rosuvastatin on the production and activation of matrix metalloproteinase-2 and migration of cultured rat vascular smooth muscle cells induced by homocysteine“Intensive lipidlowering therapy rosuvastatin or atorvastatin, or atorvastatin + ezetimibe combination therapy) decreased Hcy levels, lipid peroxidation and LDL-C levels [1].”
“CONCLUSIONS Ro uvastatin co uld inhibit Hcy in duced VSMCs dedifferentiation via suppressing ERS, which might be regulated by mTOR-P70S6K signaling.”
[Effects of rosuvastatin in homocysteine induced mouse vascular smooth muscle cell dedifferentiation and endoplasmic reticulum stress and its mechanisms].
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