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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Homocysteine and Rosiglitazone

Research Papers that Mention the Interaction

Conversely, rosiglitazone decreases Hcy levels in this time period.
During rosiglitazone treatment, Hcy levels decreased by -0.92 micromol/l; folate and vitamin B(12) levels remained unchanged.
Journal of diabetes and its complications  •  2007  |  View Paper
Rosiglitazone reduces the NF-kappaB-mediated sICAM-1 and TNF-alpha production induced by Hcy via inhibition of ERK(1/2)/p38MAPK pathway.
Biochemical and biophysical research communications  •  2007  |  View Paper
Hcy (100 micromol/L) produced a 3-fold increase in proliferation of rat aortic vascular smooth muscle cells; this augmentation was inhibited by incorporating rosiglitazone (10 micromol/L).
Rosiglitazone treatment significantly ( P < .001) suppressed Hcy levels and increased the activity of the Hcy metabolizing enzyme, cystathionine-beta-synthase in the liver samples.
Metabolism: clinical and experimental  •  2005  |  View Paper